Santa Cruz County’s 2026 watch list marks a shift from invention to execution. These companies are scaling with real organizational maturity, durable advantages, and clear catalysts, while staying anchored locally. From aviation and fintech to climate systems and biotech delivery, Santa Cruz is proving it can build globally and keep value here.

Santa Cruz Ventures proudly announces investing in Real Seq BioSciences and Calorify, pushing forward its mission through groundbreaking technology and science. Real Seq BioSciences leads in RNA diagnostics, while Calorify innovates in metabolic measurement, marking significant advancements in healthcare and precision medicine.

Big news on the bioscience block: RealSeq Biosciences, Inc., a Santa Cruz company harnessing the power of RNA fragmentomics for real-time disease diagnostics, has just announced the successful completion of a rather buoyant seed funding round.

Santa Cruz biotech company RealSeq was selected as one of 6 finalists to compete for a whopping $250K prize in the BioTools Innovator CapStone Event on October 13, 2022..

RealSeq Biosciences is in the running for a large cash prize and they need your help!

RealSeq has recently expanded its research capabilities and is currently seeking investors for a seed funding round to further support this exciting work.

Santa Cruz is booming with new startups. Join us for: Rosemary Menard / Director of Water City of Santa Cruz, Seeds Renewables, RealSeq, DoorFinder, Project Unicorn, Akkio, Waygate